However, note that a raw ISO is not always the preferred format for Xbox 360 emulation. Many users convert ISOs to other formats like GOD (Game on Demand) or extracted folder structures for better compatibility with emulators like .
Once you have the game files (typically a .iso file or a folder containing a default.xex executable), you can play it on PC using the emulator. Ninja Gaiden 2 Xbox 360 Iso