According to thermodynamic principles, the solubility of most solid compounds increases with temperature. This allows the solvent to hold a higher concentration of the target solute before reaching saturation.
Increased solubility reduces the total volume of solvent needed.
Solid material is loaded into perforated buckets attached to a continuous conveyor loop. Hot solvent is sprayed over the baskets, extracting the solute as the matrix moves through the machine. Agitated Vessel Extractors
| Advantages | Disadvantages | | :--- | :--- | | Highly reproducible and well-established method | Very slow; can take 18-24 hours | | Simple and inexpensive to set up | Uses large volumes of solvent, which is costly and wasteful | | Requires little user intervention once running | Extraction is limited to the solvent's boiling point at atmospheric pressure |
[Solid Matrix + Hot Solvent] │ ▼ ┌───────────────────────────────┐ │ Mass Transfer Zone │ ◄── Heat Applied └───────────────────────────────┘ │ ▼ ┌───────────────────────────────┐ │ Solid-Liquid Separation Step │ (Filtration/Centrifugation) └───────────────────────────────┘ │ ▼ [Extract / Micelle] + [Spent Solids / Raffinate] Soxhlet Extraction (Laboratory Scale)
Solid Liquid Extraction Hot →
According to thermodynamic principles, the solubility of most solid compounds increases with temperature. This allows the solvent to hold a higher concentration of the target solute before reaching saturation.
Increased solubility reduces the total volume of solvent needed. solid liquid extraction hot
Solid material is loaded into perforated buckets attached to a continuous conveyor loop. Hot solvent is sprayed over the baskets, extracting the solute as the matrix moves through the machine. Agitated Vessel Extractors Solid material is loaded into perforated buckets attached
| Advantages | Disadvantages | | :--- | :--- | | Highly reproducible and well-established method | Very slow; can take 18-24 hours | | Simple and inexpensive to set up | Uses large volumes of solvent, which is costly and wasteful | | Requires little user intervention once running | Extraction is limited to the solvent's boiling point at atmospheric pressure | According to thermodynamic principles
[Solid Matrix + Hot Solvent] │ ▼ ┌───────────────────────────────┐ │ Mass Transfer Zone │ ◄── Heat Applied └───────────────────────────────┘ │ ▼ ┌───────────────────────────────┐ │ Solid-Liquid Separation Step │ (Filtration/Centrifugation) └───────────────────────────────┘ │ ▼ [Extract / Micelle] + [Spent Solids / Raffinate] Soxhlet Extraction (Laboratory Scale)
